Just started helping my friend try to figure this one out...

Car: 355, joe o cam, lloyd heads, LTs, 1.6s, etc

He replaced:
OPTI (3 times)
ignition coil
coil module
wires
plugs

Problem:
Car feels pretty strong, but is definitely missing slightly, the problem just all the sudden started happening, and when it started it was REAL bad, felt like 4 wires crossed, after he replaced the opti nothing happened. I noticed that the ground wire on the battery was loose, and after i fixed that it ran better, we replaced the plugs and it ran even better, but still not up to par. this is where were at now, about to reflash computer to see what happens then.